Abstract

A single channel microfluidic electrolysis cell based on inexpensive materials and fabrication techniques is described. The cell is characterised using the electrochemistry of the Fe(CN)63−/Fe(CN)64− couple and its application in electrosynthesis is illustrated using the methoxylation reactions of N-formylpyrrolidine and 4-t-butyltoluene. It is shown that the reactions can be carried out with a good conversion in a single pass. The device, as described, allows the production of several mmol/hour of the methoxylated products.

Keywords

  • Microflow reactor;
  • Electrolysis cell;
  • Methoxylation reactions
Full-size image (50 K)

Fig. 1. Schematic illustration of the microflow reactor showing the essential components of the electrolysis cell. The diameter of the electrodes was 100 mm. The cell was sealed under compression by 11 stainless steel bolts placed in insulating tubes.

Full-size image (35 K)

Fig. 2. Schematic of the experimental set up, where 1 – the solvent bottle, 2 – pump, 3 – 5 ml sample loop, 4 – microreactor, and 5 – collection vial.

SOURCE:   http://www.sciencedirect.com/science/article/pii/S0013468611000971

Advertisements